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Combining new data-collection tools and improved beam delivery on the macromolecular crystallography beamline I04 at Diamond Light Source

MetadataDetails
Publication Date2017-05-26
JournalActa Crystallographica Section A Foundations and Advances
AuthorsRalf Flaig, Pierpaolo Romano, Jonathan Blakes, Chris Bloomer, Graham Duller
InstitutionsDiamond Light Source
AnalysisFull AI Review Included

Technical Documentation & Analysis: High-Precision Diamond Components for Macromolecular Crystallography Beamlines

Section titled “Technical Documentation & Analysis: High-Precision Diamond Components for Macromolecular Crystallography Beamlines”

Reference: Combining new data collection tools and improved beam delivery on the macromolecular crystallography beamline I04 at Diamond Light Source (Flaig et al., Acta Cryst. (2017). A73, a71)


6CCVD analyzes the I04 beamline upgrade at Diamond Light Source, identifying critical opportunities where high-purity MPCVD diamond is essential for achieving next-generation performance in X-ray optics and beam diagnostics.

  • Application Focus: Upgrades to the I04 Macromolecular Crystallography (MX) beamline require enhanced stability and precision to handle increasingly challenging, small-sized samples.
  • Precision Requirement: The system must reliably deliver and monitor beam sizes down to 10 ”m (horizontal) x 5 ”m (vertical).
  • Critical Components: Key hardware upgrades include a new Double Crystal Monochromator (DCM) and advanced beam position/intensity monitors.
  • Material Necessity: Future operational changes (increased ring current, lower emittance, higher power insertion devices) mandate materials with extreme thermal stability and radiation hardness.
  • 6CCVD Solution: High-purity, low-birefringence Single Crystal Diamond (SCD) is the industry standard for high-heat load X-ray monochromators and windows, ensuring minimal thermal distortion.
  • Diagnostic Opportunity: Boron-Doped Diamond (BDD) or high-purity SCD plates are ideal for robust, high-resolution beam position and intensity monitors operating under high flux.

The following data points extracted from the research paper define the operational environment and component requirements for the I04 beamline upgrades:

ParameterValueUnitContext
Beamline ApplicationI04N/AMacromolecular Crystallography (MX)
Energy Range (Tuneable)5 - 25keVWide operational range for SAD/MAD experiments
Energy Range (Core)6 - 17keVStandard operating range
Minimum Beam Size (H x V)10 x 5”mAchieved via compound refractive lenses (CRL)
Maximum Beam Size (H x V)110 x 100”mCRL adjustment range
Monochromator TypeDouble Crystal Monochromator (DCM)N/ANewly installed, designed for enhanced stability
Future Power DemandIncreasedN/AAnticipated due to higher ring current and new insertion devices
Required Beam DeliveryReliable, stringent intensity and positionN/ANecessary for small sample sizes

The I04 beamline improvement program focuses on hardware and software integration to enhance beam delivery reliability and data collection efficiency.

  1. Beam Focusing System: Installation of an array of compound refractive lenses in a transfocator-like device, enabling rapid, wide-range adjustment of beam size (10x5 ”m to 110x100 ”m).
  2. Monochromator Upgrade: Implementation of a new, in-house designed Double Crystal Monochromator (DCM) based on proven technology, specifically engineered for increased stability under future high-power conditions.
  3. Beam Diagnostics and Feedback: Commissioning of new beam position and intensity monitors designed to integrate with a beam delivery feedback system for real-time stabilization.
  4. Goniometry Improvement: Planning for the installation of the SmarGon multi-axis goniometer to facilitate faster sample centring, improved helical scan performance, and multi-sweep data collection strategies.
  5. Software Development: Ongoing work on the user software interface to streamline and optimize complex user experiments.

The stringent requirements for thermal management, radiation hardness, and optical quality in synchrotron X-ray optics and diagnostics are perfectly matched by 6CCVD’s MPCVD diamond capabilities.

To replicate or extend the performance of the I04 beamline components, 6CCVD recommends the following materials:

Component ApplicationMaterial RecommendationKey 6CCVD SpecificationRationale
High-Heat Load Monochromator Crystals (DCM)Optical Grade SCD (Single Crystal Diamond)SCD thickness 100 ”m - 500 ”m; Ra < 1 nm polishing.Highest thermal conductivity (22 W/cm·K) minimizes thermal distortion under high flux. Low defect density ensures optimal diffraction efficiency.
Beam Position/Intensity MonitorsHigh-Purity SCD or Boron-Doped Diamond (BDD)SCD or PCD plates up to 125mm; Custom metalization (Au/Pt).Radiation hardness and fast charge carrier mobility are critical for reliable, high-speed beam diagnostics. BDD offers uniform conductivity for sensor applications.
X-ray Windows/FiltersOptical Grade SCD or PCDSCD thickness 50 ”m - 150 ”m.Low Z material minimizes absorption while providing robust vacuum separation against high pressure differentials.

6CCVD provides the necessary engineering flexibility to supply components tailored precisely to synchrotron specifications, ensuring seamless integration into existing beamline infrastructure like the I04 DCM and diagnostic systems.

  • Custom Dimensions: We offer SCD and PCD plates/wafers up to 125mm in diameter, accommodating large-area diagnostic requirements.
  • Precision Thickness Control: SCD and PCD layers can be grown and processed to precise thicknesses ranging from 0.1 ”m up to 500 ”m, essential for optimizing X-ray absorption and diffraction characteristics.
  • Advanced Polishing: We guarantee ultra-low surface roughness (Ra < 1 nm for SCD; Ra < 5 nm for inch-size PCD), critical for minimizing scattering losses in X-ray optics.
  • Integrated Metalization: 6CCVD offers in-house metalization services, including deposition of Au, Pt, Pd, Ti, W, and Cu. This capability is vital for creating ohmic contacts, electrodes, and bonding layers required for beam position monitors and detector arrays.

6CCVD’s in-house PhD team specializes in the application of MPCVD diamond for high-energy physics and synchrotron optics. We can assist beamline engineers in material selection, orientation, and thermal modeling for similar High-Heat Load X-ray Optics and Beam Diagnostics projects. Our expertise ensures that the diamond material selected meets the stringent stability and power handling requirements necessitated by future increases in ring current and insertion device power output.

For custom specifications or material consultation, visit 6ccvd.com or contact our engineering team directly.

View Original Abstract

Diamond Light Source [1] currently operates five beamlines for macromolecular crystallography (MX) and soon seven beamlines will serve the MX user community [2].I04, a widely tuneable (5-25 keV, core range 6-17 keV) SAD/MAD station [3] is constantly evolving with the aim to provide the user with state of the art tools for data collection, especially to enable structure solution from increasingly difficult and challenging samples.Since early 2015 the beamline is using an array of compound refractive lenses in a transfocator like device allowing the user to quickly change the beam size from 10 (h) x 5 (v) up to 110 (h) x 100 (v) microns over a wide energy range and thus be better able to match the beam size to the crystal size or be able to select more precisely the best part of the crystal.Using these small beam sizes, especially with small sample sizes, requires much more stringent schemes in terms of reliable beam delivery with respect to beam intensity and position than were envisaged for the original beamline design, including the monochromator and beam diagnostics.We therefore have started a programme to improve beam delivery and have recently installed a new double crystal monochromator (DCM) which was designed inhouse based on existing proven technology and experience gained from other designs.The aim is to provide a system that is more stable, also taking into account possible future changes e.g. an increase in ring current, a lower emittance storage ring lattice and a new insertion device with higher power output.Alongside this, we have installed new beam position and intensity monitors that we are currently commissioning to be used in conjunction with a beam delivery feedback system.We are also looking into an improved goniometry and sample test system.As part of this we are planning the installation of the SmarGon multi-axis goniometer, which will enable better and faster sample centring, improved helical scan performance and provide users with new scientific capabilities for multi-sweep data collection strategies using multiple crystal orientations.Alongside these upgrades in beamline hardware we are also working on the development of the user software interface in order to streamline the user experiments.